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Our Commitment To Progesterone Receptor Positive (PR+) Cancer Patients

At Context Therapeutics, we are passionate about improving health and committed to helping people with cancer.   To fulfill our promise to patients, we have created the ONWARD Clinical Trial network to evaluate our investigational product, Apristor (onapristone xr) in PR+ breast, ovarian, and endometrial cancers.  



Phase 2/3 Combo Trial
HR+ Breast Cancer

ONWARD 201 will evaluate Apristor in second line (2L) metastatic breast cancer patients who are hormone receptor positive (HR+) and who have failed first line Cdk4/6 inhibitor therapy,


Phase 2 Trial
PR+ Breast Cancer

ONWARD 203 will evaluate Apristor in a pre-surgical, window of opportunity study in treatment naive PR+ breast cancer patients.


Phase 2 Basket Trial
PR+ Gynecologic Cancers

ONWARD 220 will evaluate Apristor in chemotherapy resistant ovarian and endometrial cancer patients.

Investigator Sponsored TRIALS

At Context Therapeutics, we are committed to the advancement of medical and scientific knowledge that addresses the unmet needs of patients with hormone driven cancers.  

To learn more about our ISTs, click here.