Mr. Lehr is the Co-founder and CEO of Context Therapeutics. In addition, Mr. Lehr is a member of the Scientific Advisory Board of Integral Molecular, an antibody discovery company. Previously, Martin was part of the founding team at Osage University Partners, a venture capital fund focused on academic spinouts from leading research institutions. At Osage, Martin focused on early stage oncology and rare disease opportunities. Prior to Osage, Martin conducted research at the Sloan Kettering Institute in DNA repair and at the Children’s Hospital of Philadelphia in thrombosis and hemostasis. In addition to his role at Context, Martin is the Director of Philly BioBreak, a biotech executive peer group with over 2,500 active members across the United States. He holds an M.A. in Biotechnology from Columbia University and a B.A. in Economics from the University of Pennsylvania.Read More
Scott Applebaum is a high-impact, strategic executive with deep global experience and demonstrated operational success leading legal, commercial, and regulatory functions for small and large life sciences companies. Scott joins Context Therapeutics from Vitae Pharmaceuticals, where he was General Counsel & Corporate Secretary at the time of its sale to Allergan. Prior to Vitae, Scott was Chief Legal Officer & Corporate Secretary for Medgenics, Inc., a clinical stage, publicly traded biotech. Scott previously spent 10 years as Senior Vice President at Shire Pharmaceuticals, where he led the strategy and execution of three key functions – commercial, legal, and regulatory. Before joining Shire, Scott spent seven years in progressive legal positions at Bristol-Myers Squibb, and he began his career as an Associate in the Corporate Tax Department at Dechert LLP.
Scott earned a Juris Doctor from Stanford Law School, where he was an editor of the law review, and a B.S. in Economics from the Wharton School, University of Pennsylvania. He is a member of the Pennsylvania and New Jersey bars, and is a certified public accountant.Read More
Dr. Jean-Pierre (“JP”) Bizzari currently is a member of the Board of Directors of Halozyme, Nordic Nanovector Onexeo, Transgene, and previously of Celator Pharmaceuticals (acquired by Jazz Pharmaceuticals). JP has been involved in the clinical development of several anticancer agents such as Taxotere®, Eloxatin®, Abraxane®, Irinotecan® (CPT-11). As a world-renowned oncology expert, he is a member of the Scientific Advisory Board of the French National Cancer Institute (INCa) and European Organization of Research and Treatment of Cancer (EORTC) and Chairman of the New Drug Advisory Committee. Prior to serving as an advisor to emerging biotechnology companies, JP served as EVP and Group Head of Clinical Oncology Development (U.S., Europe, and Asia/Japan) at Celgene (2008-2015). Previously, JP served as VP of Clinical Oncology Development at Sanofi-Aventis (2002-2008), VP of Clinical Oncology at joined Rhône-Poulenc Rorer (1993-2002), and Head of Oncology at Servier (1983-1993). He holds an M.D. specialized in oncology from the University of Nice (France) and has trained successively at the Pitié-Salpêtrière hospital in Paris, at Ontario Cancer Institute, and Montreal McGill Cancer Center in Canada.Read More
Dr. Scott Dax is a Senior Advisor to Context focusing on medicinal chemistry. In addition to his role at Context, Scott is a Co-founder of CerSci Therapeutics and is a Project Manager at BioMotiv, an early stage venture capital fund. Previously, Scott served as Chief Technology Officer at Galleon Pharmaceuticals, a venture-backed startup focused on developing therapeutics to treat narcotic-induced respiratory depression and sleep apnea. Prior, Scott served as Analgesics Research Team Leader at Johnson & Johnson where he gained extensive experience in the Sigma1 field. Earlier in his career, Scott held positions of increasing responsibility at DuPont-Merck and Hoffmann-LaRoche. Scott is an inventor of over 100 issued patents and 100 publications and presentations in peer-reviewed journal and professional societies. He holds an M.S. and Ph.D. in Chemistry from the University of Michigan and completed his postdoctoral training at the University of Wisconsin.Read More
Mr. Morris is an accomplished senior finance executive who has spent over 20 years in the life science industry, most recently as Chief Financial Officer of Vitae Pharmaceuticals, which was acquired by Allergan PLC for $639 million in November 2016. In this capacity, he led the company’s multiple public offerings and raised over $130 million. Prior to Vitae, Rich spent 12 years at ViroPharma Incorporated. He was Vice President - Financial and Strategic Planning when the company was acquired for $4.2 billion by Shire Pharmaceuticals. In addition to leading finance teams in the US, Rich provided finance leadership for multiple product launches, product in-licensing and acquisitions and oversight for European operations and was a member of the company’s European Business Unit Board and of the International Business Unit Board.
Rich began his career with KPMG, LLP in their Healthcare and Life Science practice. Rich holds a Bachelor of Science degree in Accounting from Saint Joseph’s University in Philadelphia and is a Certified Public Accountant in the state of Pennsylvania.Read More
Dr. Felix Kim is the Co-founder, Chief Scientific Officer, and Chair of Scientific Advisory Board of Context Therapeutics. In addition, Felix is currently an Assistant Professor in the Department of Pharmacology & Physiology at Drexel University College of Medicine and is Secretary/Treasurer of the Translational and Clinical Pharmacology division of the American Society for Pharmacology and Experimental Therapeutics (ASPET). Prior to receiving his faculty position at Drexel, Felix completed a Post-Doctoral Fellowship with Dr. Gavril Pasternak at the Memorial Sloan Kettering Cancer Center. Felix is a leading authority on Sigma1 biology, having authored some of the seminal works in the field. He holds a Ph.D. in Biochemistry from Universitè Montepellier (France) and a B.S. in Biology from University of California San Diego.Read More
Dr. Kim is Co-founder and Head of Sigma1 Program. In addition, Felix currently serves as a Member of the Sidney Kimmel Cancer Center at Thomas Jefferson University, Assistant Professor at Drexel University, and Secretary/Treasurer of the Translational and Clinical Pharmacology division of the American Society for Pharmacology and Experimental Therapeutics (ASPET). He is an expert in the pharmacology and biology of Sigma1 in cancer and in Sigma1 drug discovery. He has produced novel technologies and small molecule compounds used by scientists around the world to elucidate the role of Sigma1 in disease. He holds a BS in Biochemistry & Cell Biology from the University of California at San Diego, a PhD in Biochemistry from the Université de Montpellier (France) for work performed at the Centre National de la Recherche Scientifique, and performed a post-doctoral fellowship in the Molecular Pharmacology & Chemistry Program at Memorial Sloan Kettering Cancer Center.Read More
Dr. Evan Dick is currently SVP of Discovery Medicine at Aclaris Therapeutics, a publicly-traded dermatology company, and a Partner at NeXeption, a therapeutic incubator. Previously, Evan was SVP of Chemistry at Ralexar Therapeutics, a venture-backed autoimmune startup. Prior, Evan served as SVP of R&D or BD at multiple successful venture-backed startups, including Ceptaris Therapeutics (acquired by Actelion), Ception (acquired by Cephalon), and Fulcrum Pharmaceuticals (acquired by Ception). Evan gained additional startup experience at Kereos, MedStrategy, and Cytotaxis. Prior, Evan was Head of Ophthalmology R&D at G.D. Searle & Company. Evan was also an Assistant Professor in the Departments of Ophthalmology and Pharmacology at the Washington University School of Medicine. He earned a B.S. from Cornell University and Ph.D. from SUNY Buffalo.Read More
Dr. Ford-Hutchinson is currently a Board Member or Scientific Advisor to multiple startup companies and private foundations. Tony has over 30 years of experience in pharmaceuticals, including an extensive tenure at Merck & Co. At Merck Frosst, Canada, Tony led teams that developed Singulair®, Cox-2 inhibitors (Vioxx® and Arcoxia®), prostaglandin DP receptor antagonist (a component of Tredaptive®) and Cat K inhibitors (odanacatib) making the Merck Frosst Laboratories the most productive discovery unit of Merck. Subsequent career highlights at Merck relating to infectious disease include the development of HIV integrase inhibitor Isentress® and development & licensing of therapies to tackle drug-resistant bacterial infections. Tony's most recent responsibility at Merck as head of Vaccine R&D led to commercialization of 4 vaccines; Gardasil®, Zostavax®, Proquad® and Rotateq®. Tony is Chairman of the Board of Directors, MSD Wellcome Trust Hilleman Labs, Board of Trustees, and President, Merck Genome Research Institute.Read More
Mr. Lehr is the Co-founder and CEO of Context Therapeutics. In addition, Mr. Lehr is a member of the Scientific Advisory Board of Integral Molecular, an antibody discovery company. Previously, Martin was part of the founding team at Osage University Partners, a venture capital fund focused on academic spinouts from leading research institutions. At Osage, Martin focused on early stage oncology and rare disease opportunities. Prior to Osage, Martin conducted research at the Sloan Kettering Institute in DNA repair and at the Children’s Hospital of Philadelphia in thrombosis and hemostasis. In addition to his role at Context, Martin is a Director of BioBreak, a biotech executive peer group with over 2,500 active members across the United States. He holds an M.A. in Biotechnology from Columbia University and a B.A. in Economics from the University of Pennsylvania.Read More
Dr. Martin Phillips is currently Co-Founder and CEO of Opsidio, a fibrosis-focused startup. In addition, Martin is also CEO of Tarnhelm Therapeutics, an Advisor to Integral Molecular, and on the Steering Committee of Mid-Atlantic BioAngels. Martin brings nearly 30 years of experience including a career in academic medicine, biotech and the pharmaceutical industry. Previously, Martin served as the Chief Medical Officer at two venture-backed startups: Morphotek (acquired by Eisai), an antibody discovery platform; and a Millendo Therapeutics, a rare disease drug discovery company. Prior, Martin was VP of Clinical R&D at Aventis Behring, an Assistant Professor of Medicine at Baylor College of Medicine, and an Associate Professor at University of Texas-Houston. He holds an M.D. from Wayne State University School of Medicine and a B.S. from the University of Michigan.Read More
Dr. Sorensen is President and Chief Executive Officer and Board Director of Galera Therapeutics. Mel is a Medical Oncologist who has spent 7-8 years each in patient care (including his oncology fellowship at the Mayo Clinic), in academia (at the National Institutes of Health), in leadership positions in clinical development in the pharmaceutical industry (GlaxoSmithKline and Bayer), and as President & CEO of private venture-funded biotechs, including Ascenta Therapeutics and Galera Therapeutics. He also serves as Chairman of other biotech companies, including OncoFusion Therapeutics. At Ascenta, Mel raised approximately $100 million in private financing and venture debt and secured global and regional deals for its three programs. Operationally, in about five years, Ascenta advanced two unrelated preclinical programs into broad clinical testing, managed multiple clinical trials, and developed an R&D presence in China. Mel is an advisor to the Biomarkers Consortium of the National Institutes of Health.Read More
Dr. Ulrich is currently a Senior Advisor to Frazier Healthcare Partners. In addition, Roger on the Board of Directors of Remedy Pharmaceuticals, Aminex, and is a Scientific Advisor to Mllendo Therapeutics. Previously, Roger was Chief Scientific Officer of Acerta Pharma (acquired by AstraZeneca) and Co-founder and Chief Development Officer of Calistoga Pharmaceuticals (acquired by Gilead). Prior to Calistoga, Roger was Senior Scientific Director with Merck Research Laboratories and Director of Drug Safety Evaluation at Abbott Laboratories. Earlier, Roger was a Senior Scientist with both The Upjohn Company and Pharmacia & Upjohn Inc. Roger has authored more than 120 publications and is a Fellow of the Academy of Toxicological Sciences. He holds a Ph.D. in Cellular and Molecular Biology from West Virginia University.Read More
Dr. Kantoff is the Chairman of the Department of Medicine at Memorial Sloan Kettering Cancer Center in New York, which is the leading development and testing center for novel cancer therapies. He also served as Director of The Lank Center for Genitourinary Oncology, Chief of the Division of Solid Tumor Oncology, Vice Chair of the Department of Medical Oncology, and Chair of the Executive Committee on Clinical Research at the Dana-Farber Cancer Institute. He is a Professor Emeritus of Medicine at Harvard Medical School, the Chairman of the Global Treatment Science Network of the Prostate Cancer Foundation, and member of numerous professional societies and editorial boards. Dr. Kantoff published more than 350 research articles on a variety of topics, written nearly 100 reviews and monographs on cancer and has edited numerous books, including Prostate Cancer, A Multi-Disciplinary Guide published by Blackwell, and Prostate Cancer: Principles and Practice, a definitive text on prostate cancer.Read More
Dr. Knudsen is the Director of the Sidney Kimmel Cancer Center at Thomas Jefferson University. Karen serves on a multitude of national scientific advisory boards and committees, including those for the National Institutes of Health (NIH), American Association for Cancer Research, the Endocrine Society, and the Prostate Cancer Foundation. She is the Editor-in-Chief of Molecular Cancer Research, a senior editor for Cancer Research, and is on the editorial boards of Molecular Cancer Therapeutics, Endocrine-Related Cancer, American Journal of Pathology, Molecular Endocrinology, and Oncogene. Karen has received numerous awards for her research, including the Ronald Ross Award for Excellence in hormone-dependent malignancies from the Pacific Rim Breast and Prostate Cancer Research Organization and the Richard E. Weitzman Laureate Award from the Endocrine Society. Karen’s research identifying tumor suppressor and hormone receptor alterations have uncovered new targets for treating advanced disease, and led to the development of several innovative biomarker-driven clinical trials. Karen received a BS in Biology from The George Washington University, a PhD in Molecular Biology from the University of California at San Diego, and performed a post-doctoral fellowship at the Ludwig Institute for Cancer Research.Read More
Dr. Kruse is Assistant Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. In 2016, Andrew’s group published in Nature the first crystal structure of Sigma1. His research focuses on the molecular basis of transmembrane signaling through pharmacology and structural biology. This work was recently described as a “landmark achievement for molecular pharmacology and drug discovery” (F1000Prime review by Bryan Roth, UNC Chapel Hill). Andrew has received multiple prestigious awards, including the Sloan Research Fellowship (2017), Forbes 30 under 30 (2016), and the NIH Director’s Early Independence Award (2015). He holds bachelor’s degrees in Biochemistry and Mathematics from the University of Minnesota and a PhD in Structural Biology from Stanford University.Read More
Dr. Montgomery is Professor of Medicine, University of Washington School of Medicine, is Clinical Director of Genitourinary Medical Oncology at the Seattle Cancer Care Alliance, and is a GU oncologist with the Veterans Affairs Puget Sound Health Care System. Bruce has lead numerous genitourinary cancer clinical trials and specializes in the treatment of high risk and advanced prostate cancer and drug resistance to hormonal therapy and taxane chemotherapy. He holds an MD from Duke University School of Medicine, and he performed his residency at Brigham and Women’s Hospital and an oncology fellowship at the University of Washington School of Medicine.Read More
Dr. Mostaghel is Associate Member of the Clinical Research Division at Fred Hutchinson Cancer Research Center and Associate Professor of Medical Oncology Division at the University of Washington School of Medicine. Elahe is a genitourinary oncologist who has lead multiple translational research programs on the development of strategies to treat hormone refractory prostate cancer and is involved in clinical trials for all phases of prostate cancer therapy. She is a program leader in the Pacific Northwest Prostate Cancer Specialized Programs of Research Excellence (SPORE). She holds AB in Biology from Harvard University, a PhD in immunology and MD from Duke University, and performed her residency at the University of California at San Francisco and an oncology fellowship at the Fred Hutchinson Cancer Research Center.Read More
Dr. Tasir Haque is Head of Chemistry at Context Therapeutics. Prior to joining Context, Tas was a Principal Scientist in Immunology Chemistry at Bristol-Myers Squibb, where he focused on advancing small molecule programs to IND status. His background at BMS includes drug discovery programs in several therapeutic areas including Oncology, Metabolic Diseases, and Cardiovascular Diseases. Tas has extensive experience with both small molecule and linear and cyclic peptide research. Earlier in his career, Tas was a member of the Directed Parallel Synthesis medicinal chemistry team at DuPont Pharmaceuticals, where he focused on Anti-Infectives. Tas is an inventor on multiple patents and has written and reviewed articles in several peer-reviewed journals. He holds a B.S. in Chemistry from the University of Michigan, a Ph.D. in Organic Chemistry from the University of Wisconsin, and was an NIH postdoctoral fellow at the University of California, Berkeley.Read More
Dr. Lala has 20 years of drug discovery experience at a strategic and operational level in large and small pharmaceutical companies. Before Context he was Executive Director, Biology at Vitae Pharmaceuticals (affiliate of Allergan Inc.) where he played a key role in advancing seven compounds into clinical studies (Phase I/II) for multiple indications. He was also responsible for building and executing translational biomarker approaches for human proof of mechanism studies. Before Vitae, he was Associate Director at Pfizer where he led an anti-fibrosis program leading to a clinical candidate and demonstrating the translatability of preclinical fibrotic biomarkers in the clinic. Prior to that he was a Group Leader at Pharmacia where he created a drug discovery platform to initiate new programs across different therapeutic areas. Before that he worked at Ligand Pharmaceuticals focusing on nuclear receptors as drug targets. Dr. Lala earned his Ph.D. in Cell and Molecular Biology from Augusta University. He was awarded a Howard Hughes Medical Institute (HHMI) fellowship to carry out post-doctoral training at Duke University Medical Center.